Cerebral Venous Sinus Thrombosis with MTHFR C677T Heterozygous Mutation
نویسندگان
چکیده
Decrease in the activity of methylenetetrahydrofolate reductase (MTHFR) increases level homocysteine. MTHFR C677T gene polymorphism has been reported as a well-known cause elevated homocysteine associated with cerebral venous sinus thrombosis (CVST). A 34-year-old male was admitted severe headache after generalized seizure. Brain magnetic resonance venography showed thrombus superior sagittal sinus. In investigation risk factors, slight increase caused by heterozygous mutation is presumed to be CVST.
منابع مشابه
Heterozygous MTHFR A1298C Mutation causing Cerebral Venous Sinus Thrombosis.
A 21 year college student came with a history of generalized tonic-clonic seizures. MR Venography revealed the presence of left sigmoid and transverse sinus thrombosis with secondary venous hemorrhagic infarcts. After thorough investigation into cause of thrombosis patient was found to have a heterozygous MTHFR A1298C mutation which was causing cerebral venous sinus thrombosis.
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ژورنال
عنوان ژورنال: Journal of the Korean neurological association
سال: 2022
ISSN: ['1225-7044', '2288-985X']
DOI: https://doi.org/10.17340/jkna.2022.4.3